Accomplishments and discoveries from VGN students and faculty

Facility Research Studies & Publications

Facility Research Projects Completed:

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Project Title:

Presented at:

Use of Novel Abrasives for the Extraction of RNA from Small Amounts of Difficult Tissue


Vermont Cancer Center Symposium,
Burlington, VT
Oct. 2005

Strategies For Generating Microarray Data From LCM Derived Breast Tissue RNA


Vermont Cancer Center Symposium,
Burlington, VT
Oct. 2006

Assessing the Affect of RNA and cDNA Freeze-Thaw Cycling on Gene Expression using Microarray and RT-qPCR


Association of Biomolecular Resource Facilities,
Salt Lake City, UT
Feb. 2008

Common Practices for Routine RNA Handling:  A Three Part Story

Association of Biomolecular Resource Facilities, Memphis, TN
Feb. 2009

Comparison of Microarray Data Generated from Degraded RNA using Five Different Target Synthesis Methods and Commercial Microarrays.


Advances in Microarray Technology,
Stockholm, SW
May 2009

Comparative Transcriptional Profiling of Asbestos ­Treated Human Mesothelial Cells:
Affymetrix HTA2.0 vs. Illumina RNA-Seq
NIH, NIGMS Fifth Biennial National IDeA Symposium of Biomedical Research Excellence (NISBRE)
Washington, DC
June 2014


Microarray August, 2005 through March, 2009

1: Sabo-Attwood T, Ramos-Nino M, Bond J, Butnor KJ, Heintz N, Gruber AD, Steele
C, Taatjes DJ, Vacek P, Mossman BT. Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis. Am J Pathol. 2005 Nov;167(5):1243-56.
PMID: 16251409 [PubMed - indexed for MEDLINE]

2: Pulver-Kaste RA, Barlow CA, Bond J, Watson A, Penar PL, Tranmer B, Lounsbury KM.  Ca2+ source-dependent transcription of CRE-containing genes in vascular smooth muscle.  Am J Physiol Heart Circ Physiol. 2006 Jul;291(1):H97-105. Epub 2006 Feb 3.  PMID: 16461377 [PubMed - indexed for MEDLINE]

3. Muthusamy, V, Duraisamy, S, Bradbury, M, Hobbs, C, Curley, DP, Nelson, B, and Bosenberg, M.   Epigenetic Silencing of Novel Tumor Supressors in Malignant Melanoma, Cancer Research; 66: (23), 11187-11193, 2006

4. Chaudhry, M., Bystander effect: biological endpoints and microarray analysis.

Mutat Res. 2006 May 11;597(1-2):98-112. Epub 2006 Jan 18. Review.

PMID: 16414093 [PubMed - indexed for MEDLINE]

5: Zheng J, Watson AD, Kerr DE.
Genome-wide expression analysis of lipopolysaccharide-induced mastitis in a mouse
model.  Infect Immun. 2006 Mar;74(3):1907-15. PMID: 16495566 [PubMed - indexed for MEDLINE]

6: Rolerson, E., A. Swick, L. Newlon, C. Palmer, Y. Pan, B. Keeshan, and G. Spatafora. 2006. The SloR/Dlg metalloregulator modulatesStreptococcus mutans virulence gene expression. J. Bacteriol. 188:5033-5044.

7: Braas KM, Schutz KC, Bond JP, Vizzard MA, Girard BM, May V.
Microarray analyses of pituitary adenylate cyclase activating polypeptide(PACAP)-regulated gene targets in sympathetic neurons.  Peptides. 2007 Sep;28(9):1856-70. Epub 2007 Apr 19.  PMID: 17512639 [PubMed - indexed for MEDLINE]

8: Rose P, Bond J, Tighe S, Toth MJ, Wellman TL, Briso de Montiano EM, Lewinter
MM, Lounsbury KM.  Genes overexpressed in cerebral arteries following salt-induced hypertensive
disease are regulated by angiotensin II, JunB, and CREB.  Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H1075-85. Epub 2007 Dec 21.  PMID: 18156195 [PubMed - indexed for MEDLINE]

9: Finucane KA, McFadden TB, Bond JP, Kennelly JJ, Zhao FQ.  Onset of lactation in the bovine mammary gland: gene expression profiling indicates a strong inhibition of gene expression in cell proliferation.
Funct Integr Genomics. 2008 Aug;8(3):251-64. Epub 2008 Feb 8. PMID: 18259788 [PubMed - indexed for MEDLINE]

10: Alcorn JF, Guala AS, van der Velden J, McElhinney B, Irvin CG, Davis RJ,
Janssen-Heininger YM.  Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by  TGF-beta1.  J Cell Sci. 2008 Apr 1;121(Pt 7):1036-45. Epub 2008 Mar 11.  PMID: 18334556 [PubMed - indexed for MEDLINE]

11: Rand MD, Bland CE, Bond J.  Methylmercury activates enhancer-of-split and bearded complex genes independent of the notch receptor.  Toxicol Sci. 2008 Jul;104(1):163-76. Epub 2008 Mar 25.
PMID: 18367466 [PubMed - indexed for MEDLINE]

12: Casey T, Bond J, Tighe S, Hunter T, Lintault L, Patel O, Eneman J, Crocker A, White J,
Tessitore J, Stanley M, Harlow S, Weaver D, Muss H, Plaut K.  Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer.  Breast Cancer Res Treat. 2008 Mar 29. [Epub ahead of print]PMID: 18373191 [PubMed - as supplied by publisher]

13: Bove PF, Hristova M, Wesley UV, Olson N, Lounsbury KM, van der Vliet A.
Inflammatory levels of nitric oxide inhibit airway epithelial cell migration by inhibition of the kinase ERK1/2 and activation of hypoxia-inducible factor-1 alpha.  J Biol Chem. 2008 Jun 27;283(26):17919-28. Epub 2008 Apr 18.  PMID: 18424783 [PubMed - indexed for MEDLINE]

14: Lu C, Pelech S, Zhang H, Bond J, Spach K, Noubade R, Blankenhorn EP, Teuscher
C.  Pertussis toxin induces angiogenesis in brain microvascular endothelial cells.  J Neurosci Res. 2008 Sep;86(12):2624-40.  PMID: 18500752 [PubMed - in process]


15: Shukla, A.,  MacPherson, M., Hillegass, J.,  Ramos-Nino, M., Alexeeva, V.,  Vacek, P.,
Bond, J., Pass, H., Steele, C.,  and  Mossman, B., (2009) Alterations in gene expression in human mesothelialcells correlate with mineral pathogenicity , American J of Respiratory Cell and Molecular Biology, in press, 2008 Dec 18. [Epub ahead of print]


16: Dienz, O., Eaton, S.M., Bond, J.P., Neveu, W., Moquin, D., Noubade, R., Briso, E.M. Charland, C., Leonard, W.J., Ciliberto, G., Teuscher, C., Haynes, L., and Rincon, M.  " The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4 T cells".  J Exp Med. 2009 Jan 16;206(1):69-78. Epub 2009 Jan 12.

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