Director, VGN Proteomics Facility
The VGN Proteomics facility has been serving our network investigators with the goal of providing the latest technology and comprehensive expertise to enhance research capacities and to establish an educational environment for sharing experience and knowledge in proteomics. Some of our exciting achievements over the years are highlighted below:
Specifically, we have enhanced our capacities in the following areas over this past year:
Establishing Proteomics Workflows We have developed a number of sample preparation workflows to characterize the networks of protein expression, post-translational modifications (e.g., phosphorylation, acetylation) and protein interactomes in complex protein mixtures. In order to enrich students’ learning experience, we are now offering closely supervised opportunities to interested individuals to carry out these experiments as well as to operate the sophisticated mass spectrometry instrumentation.
Data Analysis To efficiently handle increasingly complicated proteomic analyses; we have been working closely with the Bioinformatics Core to build new software capabilities that are housed in our Data Processing room (MLS 333). Many undergraduate and graduate students have mentioned that they benefited from analyzing their own data and enjoyed the dynamic interactions with the facility personnel!
Undergraduate Student Training. The facility has been working with several faculty from the departments of Biology, Plant Biology and Biochemistry at UVM. These faculty have successfully incorporated proteomics into their courses and laboratory curricula (PBIO 187, BIOC 207, BIO 205) aimed at equipping future scientists with state-of-the-art proteomics knowledge. Facility personnel have also given guest proteomics lectures on specific topics for a number of undergraduate and graduate UVM and BPI courses.
Our future goals are to continue providing cutting-edge expertise to network investigators as well as developing and strengthening our interactions with BPI faculty. We will be focusing on developing methodologies to target areas that represent the frontiers in proteomics applications and the future needs from our investigators. As we are exploring new collaboration opportunities with network investigators, we would love to hear from you about your research project! We want to help you solve challenging problems and will work hard to develop the best strategies to answer your proteomics questions. We look forward to working with you soon!